CEMIP Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18187-20UL
60 ul
£183.00
E-AB-18187-60UL
120 ul
£272.00
E-AB-18187-120UL
200 ul
£420.00
E-AB-18187-200UL
About this Product
- SKU:
- E-AB-18187
- Additional Names:
- IR2155535,KIAA1199 protein,OTTHUMP00000185569 ,OTTHUMP00000195036,TMEM2L,Transmembrane protein 2 like
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.68 mg/ml
- Extra Details:
- Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CEMIP
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cemip_polyclonal_antibody-e_ab_18187
