ITPR2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18139-20UL
60 ul
£183.00
E-AB-18139-60UL
120 ul
£272.00
E-AB-18139-120UL
200 ul
£420.00
E-AB-18139-200UL
About this Product
- SKU:
- E-AB-18139
- Additional Names:
- 4;5-trisphosphate receptor;5-trisphosphate receptor type 2;IP3 R2;IP3 receptor;IP3 receptor isoform 2;IP3R 2;IP3R2;ITPR 2;ITPR2;Inositol 1;Inositol 1 4 5 trisphosphate receptor type 2;Inositol 145 trisphosphate receptor type 2;InsP3 R2;InsP3R2;Itpr2;Typ
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1.86 mg/ml
- Extra Details:
- Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ITPR2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-itpr2_polyclonal_antibody-e_ab_18139
