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Antibodies

GFI1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-17997-20UL
60 ul
£183.00
E-AB-17997-60UL
120 ul
£272.00
E-AB-17997-120UL
200 ul
£420.00
E-AB-17997-200UL
About this Product
SKU:
E-AB-17997
Additional Names:
GFI 1,GFI1,Growth factor independence 1,Growth factor independent 1,Growth factor independent protein 1,SCN2,ZNF 163,ZNF163,Zinc finger protein 163,Zinc finger protein Gfi 1,Zinc finger protein Gfi-1,Zinc finger protein Gfi1
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.62 mg/ml
Extra Details:
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor.This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis.It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters.Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections.Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Host:
Rabbit
Immunogen:
Synthetic peptide of human GFI1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody