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Antibodies

HLA-DRA Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-17927-20UL
60 ul
£183.00
E-AB-17927-60UL
120 ul
£272.00
E-AB-17927-120UL
200 ul
£420.00
E-AB-17927-200UL
About this Product
SKU:
E-AB-17927
Additional Names:
DR alpha chain,DR alpha chain precursor,DRA,DRB1,DRB4,HLA ,HLA DR1B,HLA DR3B,HLA DRA,HLA DRA1,HLA DRB1,HLA DRB3,HLA DRB4,HLA class II histocompatibility antigen,HLA class II histocompatibility antigen DR alpha chain,Histocompatibility antigen HLA DR alpha
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.9 mg/ml
Extra Details:
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Host:
Rabbit
Immunogen:
Synthetic peptide of human HLA-DRA
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody