DROSHA Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-17893-20UL
60 ul
£183.00
E-AB-17893-60UL
120 ul
£272.00
E-AB-17893-120UL
200 ul
£420.00
E-AB-17893-200UL
About this Product
- SKU:
- E-AB-17893
- Additional Names:
- DROSHA,Drosha double stranded RNA specific endoribonuclease,Drosha ribonuclease type III,Etohi2,HSA242976,Nuclear RNase III Drosha,Protein Drosha,Putative protein p241 which interacts with transcription factor Sp1,Putative ribonuclease III,RANSE3L,Ri,p241
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.74 mg/ml
- Extra Details:
- This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. DROSHA (Drosha Ribonuclease III) is a Protein Coding gene. Diseases associated with DROSHA include Combat Disorder and Murray Valley Encephalitis. Among its related pathways are mRNA Capping and Gene Expression. GO annotations related to this gene include poly(A) RNA binding and RNA binding.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human DROSHA
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-drosha_polyclonal_antibody-e_ab_17893
