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Antibodies

DMGDH Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-17889-20UL
60 ul
£183.00
E-AB-17889-60UL
120 ul
£272.00
E-AB-17889-120UL
200 ul
£420.00
E-AB-17889-200UL
About this Product
SKU:
E-AB-17889
Additional Names:
Dimethylglycine dehydrogenase,Dmgdh,M2GD,ME2GLYDH,mitochondrial
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
2.1 mg/ml
Extra Details:
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Synthetic peptide of human DMGDH
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody