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Antibodies

CCL5 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-17864-20UL
60 ul
£183.00
E-AB-17864-60UL
120 ul
£272.00
E-AB-17864-120UL
200 ul
£420.00
E-AB-17864-200UL
About this Product
SKU:
E-AB-17864
Additional Names:
Beta chemokine RANTES,Beta chemokine RANTES precursor,C C motif chemokine 5,CCL 5,CCL5,Chemokine (C C motif) ligand 5,Chemokine CC Motif Ligand 5,D17S136E,EoCP,Eosinophil chemotactic cytokine,MGC17164,RANTES(4-68),Regulated upon activation normally T
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
2 mg/ml
Extra Details:
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Host:
Rabbit
Immunogen:
Synthetic peptide of human CCL5
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody