CARD16 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-17810-20UL
60 ul
£183.00
E-AB-17810-60UL
120 ul
£272.00
E-AB-17810-120UL
200 ul
£420.00
E-AB-17810-200UL
About this Product
- SKU:
- E-AB-17810
- Additional Names:
- member 16,CAR16,CARD only domain-containing protein 1,CARD only protein ,CARD16,COP,COP1,Caspase recruitment domain family,Caspase recruitment domain-containing protein 16,Caspase-1 dominant-negative inhibitor pseudo-ICE ,Caspase-1 inhibitor COP,Pseudo i
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.1 mg/ml
- Extra Details:
- Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CARD16
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-card16_polyclonal_antibody-e_ab_17810
