CACNA2D2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-17757-20UL
60 ul
£183.00
E-AB-17757-60UL
120 ul
£272.00
E-AB-17757-120UL
200 ul
£420.00
E-AB-17757-200UL
About this Product
- SKU:
- E-AB-17757
- Additional Names:
- Alpha 2 delta calcium channel subunit,CA2D2,CACNA2D,Cacna2d2,Calcium channel,Calcium voltage gated channel auxiliary subunit alpha2delta 2,Gene 26,alpha 2/delta subunit 2,alpha 2/delta subunit 2 gene 26,voltage-dependent
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CACNA2D2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cacna2d2_polyclonal_antibody-e_ab_17757
