SLC7A11 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-17625-20UL
60 ul
£183.00
E-AB-17625-60UL
120 ul
£272.00
E-AB-17625-120UL
200 ul
£420.00
E-AB-17625-200UL
About this Product
- SKU:
- E-AB-17625
- Additional Names:
- Amino acid transport system xc xCT;Amino acid transport system xc-;CCBR1;Calcium channel blocker resistance protein CCBR1;Cysteine/glutamate transporter;Cystine/glutamate transporter;OTTHUMP00000164578;SLC7
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human SLC7A11
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-slc7a11_polyclonal_antibody-e_ab_17625
