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Antibodies

VPS4A Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-17555-20UL
60 ul
£183.00
E-AB-17555-60UL
120 ul
£272.00
E-AB-17555-120UL
200 ul
£420.00
E-AB-17555-200UL
About this Product
SKU:
E-AB-17555
Additional Names:
SKD1,SKD1A,SKD2,VPS4,VPS4-1
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18.
Host:
Rabbit
Immunogen:
Synthetic peptide of human VPS4A
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody