TTI1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-17482-20UL
60 ul
£183.00
E-AB-17482-60UL
120 ul
£272.00
E-AB-17482-120UL
200 ul
£420.00
E-AB-17482-200UL
About this Product
- SKU:
- E-AB-17482
- Additional Names:
- KIAA0406;smg-10
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1.2 mg/ml
- Extra Details:
- Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human TTI1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-tti1_polyclonal_antibody-e_ab_17482
