GAD1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-17390-20UL
60 ul
£183.00
E-AB-17390-60UL
120 ul
£272.00
E-AB-17390-120UL
200 ul
£420.00
E-AB-17390-200UL
About this Product
- SKU:
- E-AB-17390
- Additional Names:
- 67 kDa glutamic acid decarboxylase,67kDa),CPSQ1,DCE1,EC 4.1.1.15,FLJ45882,GAD,GAD 67,GAD-67,GAD1,Glutamate decarboxy,Glutamate decarboxylase 1,Glutamate decarboxylase 1 (brain,Glutamate decarboxylase 1 brain 67kD,Glutamate decarboxylase 1 brain 67kDa
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes.The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid.A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes.This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human GAD1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-gad1_polyclonal_antibody-e_ab_17390
