ABCC2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-17352-20UL
60 ul
£183.00
E-AB-17352-60UL
120 ul
£272.00
E-AB-17352-120UL
200 ul
£420.00
E-AB-17352-200UL
About this Product
- SKU:
- E-AB-17352
- Additional Names:
- ABC30,ATP binding cassette sub family C (CFTR/MRP) member 2,ATP binding cassette subfamily C member 2,ATP-binding cassette sub-family C member 2,CMO,CMOAT,Canalicular multidrug resistance protein,Canalicular multispecific organic anion transporter 1,abcC2
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine, therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ABCC2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-abcc2_polyclonal_antibody-e_ab_17352
