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Antibodies

LRP6 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-17347-20UL
60 ul
£183.00
E-AB-17347-60UL
120 ul
£272.00
E-AB-17347-120UL
200 ul
£420.00
E-AB-17347-200UL
About this Product
SKU:
E-AB-17347
Additional Names:
ADCAD2,C030016K15Rik,Cd,FLJ90062,FLJ90421,LDL receptor related protein 6,LRP-6,LRP6,Low density lipoprotein receptor related protein 6,Low-density lipoprotein receptor-related protein 6,OTTHUMP00000238979,OTTHUMP00000238980,OTTHUMP00000238982,STHAG7
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.4 mg/ml
Extra Details:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Host:
Rabbit
Immunogen:
Synthetic peptide of human LRP6
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody