DUSP11 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-17232-20UL
60 ul
£183.00
E-AB-17232-60UL
120 ul
£272.00
E-AB-17232-120UL
200 ul
£420.00
E-AB-17232-200UL
About this Product
- SKU:
- E-AB-17232
- Additional Names:
- DUS11,DUSP11,Dual specificity phosphatase 11,Dual specificity protein phosphatase 11,PIR1,Phosphatase that interacts with RNA/RNP complex 1,RNA,RNA/RNP complex 1 interacting,RNA/RNP complex interacting phosphatase,RNA/RNP complex-1-interacting phosphatase
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
- Host:
- Rabbit
- Immunogen:
- Full length fusion protein
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dusp11_polyclonal_antibody-e_ab_17232
