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Antibodies

TIRAP Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-17096-20UL
60 ul
£183.00
E-AB-17096-60UL
120 ul
£272.00
E-AB-17096-120UL
200 ul
£420.00
E-AB-17096-200UL
About this Product
SKU:
E-AB-17096
Additional Names:
Adapter protein wyatt,FLJ42305,MAL,MyD88 adapter like protein,TIR domain containing adapter protein,Toll interleukin 1 receptor (TIR) domain containing adaptor protein,Toll interleukin 1 receptor domain containing adapter protein,Toll like receptor adapto
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns.Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction.The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system.It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response.Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
Host:
Rabbit
Immunogen:
Full length fusion protein
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody