TG Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-16913-20UL
60 ul
£183.00
E-AB-16913-60UL
120 ul
£272.00
E-AB-16913-120UL
200 ul
£420.00
E-AB-16913-200UL
About this Product
- SKU:
- E-AB-16913
- Additional Names:
- AITD 3,AITD3,TDH3,TGN,THYG,Tg,Thyroglobulin,hTG
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human TG
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-tg_polyclonal_antibody-e_ab_16913
