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Antibodies

SDHB Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-16795-20UL
60 ul
£183.00
E-AB-16795-60UL
120 ul
£272.00
E-AB-16795-120UL
200 ul
£420.00
E-AB-16795-200UL
About this Product
SKU:
E-AB-16795
Additional Names:
CWS2,DHSB,FLJ92337,Ip,Iron sulfur subunit,Iron sulfur subunit of complex II,Iron-sulfur subunit of complex II,PGL 4,PGL4,SDH,SDH 1,SDH1,SDH2,SDHIP,SdhB,Su,Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial,homolog of,mitochondrial
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Host:
Rabbit
Immunogen:
Synthetic peptide of human SDHB
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody