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Antibodies

TNFRSF13C Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-16646-20UL
60 ul
£183.00
E-AB-16646-60UL
120 ul
£272.00
E-AB-16646-120UL
200 ul
£420.00
E-AB-16646-200UL
About this Product
SKU:
E-AB-16646
Additional Names:
B cell activating factor receptor,B-cell-activating factor receptor,BAFF R,BAFF receptor,BAFF-R,BAFFR,BLyS receptor 3,BR 3,BR3,BROMIX,BlySR3,CD 268,CD268,CD268 antigen,CVID4,MGC138235,OTTHUMP00000028746,Prolixin,TNFRSF 13C,TR13C,Tnfrsf13c,Tumor necrosis f
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Host:
Rabbit
Immunogen:
Synthetic peptide of human TNFRSF13C
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody