CAB39 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-16615-20UL
60 ul
£183.00
E-AB-16615-60UL
120 ul
£272.00
E-AB-16615-120UL
200 ul
£420.00
E-AB-16615-200UL
About this Product
- SKU:
- E-AB-16615
- Additional Names:
- CAB39,CGI 66,CGI-66,CGI66,Cab39,Calcium binding protein 39,Calcium-binding protein 39,MO25,MO25 alpha,Mouse protein 25 alpha,Protein Mo25
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CAB39
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cab39_polyclonal_antibody-e_ab_16615
