KCNQ4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-16544-20UL
60 ul
£183.00
E-AB-16544-60UL
120 ul
£272.00
E-AB-16544-120UL
200 ul
£420.00
E-AB-16544-200UL
About this Product
- SKU:
- E-AB-16544
- Additional Names:
- DFNA 2,DFNA2,KCNQ 4,KCNQ4,KQT like 4,KQT-like 4,KV7.4,Kcnq4,Potassium channel KQT like 4,Potassium channel subunit alpha KvLQT4,Potassium voltag,Potassium voltage gated channel KQT like protein 4,Potassium voltage gated channel KQT like subfamily member 4
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.9 mg/ml
- Extra Details:
- The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human KCNQ4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-kcnq4_polyclonal_antibody-e_ab_16544
