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Antibodies

ESPL1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-16415-20UL
60 ul
£183.00
E-AB-16415-60UL
120 ul
£272.00
E-AB-16415-120UL
200 ul
£420.00
E-AB-16415-200UL
About this Product
SKU:
E-AB-16415
Additional Names:
Caspase like protein ESPL1,Caspase-like protein ESPL1,ESP 1,ESP1,ESPL 1,ESPL1,Espl1,Extra spindle poles like 1,Extra spindle poles like 1 protein,Extra spindle poles-like 1 protein,FLJ46492,KIAA0165,S,Separase,Separin,Similar to fission yeast cut1and gene
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.
Host:
Rabbit
Immunogen:
Synthetic peptide of human ESPL1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody