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Antibodies

CD40 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-16318-20UL
60 ul
£183.00
E-AB-16318-60UL
120 ul
£272.00
E-AB-16318-120UL
200 ul
£420.00
E-AB-16318-200UL
About this Product
SKU:
E-AB-16318
Additional Names:
AI326936,B cell associated molecule CD40,B cell surface antigen CD40,B cell-associated molecule,B-cell surface antigen CD40,Bp50,CD 40,CD40,CD40 antigen,CD40 antigen (TNF receptor superfamily member 5),CD40 molecule,TNF receptor superfamily
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.3 mg/ml
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily.This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, whicHuman, Mouseay be important for homotypic cell interactions.Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction.The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
Host:
Rabbit
Immunogen:
Synthetic peptide of human CD40
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody