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Antibodies

CD2AP Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-16309-20UL
60 ul
£183.00
E-AB-16309-60UL
120 ul
£272.00
E-AB-16309-120UL
200 ul
£420.00
E-AB-16309-200UL
About this Product
SKU:
E-AB-16309
Additional Names:
AL024079,Adapter protein CMS,C78928,CD2 associated protein,CD2-associated protein,CD2AP,CMS,Cas ligand with multiple SH3 domains,METS 1,Mesenchyme to epithelium transition protein with SH3 domains 1,Mets1
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.2 mg/ml
Extra Details:
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Host:
Rabbit
Immunogen:
Synthetic peptide of human CD2AP
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody