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Antibodies

PKC gamma Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-16194-20UL
60 ul
£183.00
E-AB-16194-60UL
120 ul
£272.00
E-AB-16194-120UL
200 ul
£420.00
E-AB-16194-200UL
About this Product
SKU:
E-AB-16194
Additional Names:
KPCG,MGC57564,OTTHUMP00000067291,PKC-gamma,PKCC,PKCG,PRKCG,Protein kinase C,Protein kinase C gamma,Protein kinase C gamma polypeptide,Protein kinase C gamma type,SCA 14,SCA14,gamma
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
Host:
Rabbit
Immunogen:
Synthetic peptide of human PRKCG
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody