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Antibodies

DSCR1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-16188-20UL
60 ul
£183.00
E-AB-16188-60UL
120 ul
£272.00
E-AB-16188-120UL
200 ul
£420.00
E-AB-16188-200UL
About this Product
SKU:
E-AB-16188
Additional Names:
Adapt 78;Adapt78;CSP 1;CSP1;Calcipressin 1;Calcipressin-1;Calcium and oxidant inducible mRNA;DSC 1;DSC1;DSCR 1;DSCR1;Down syndrome candidate region 1;Down syndrome critical region gene 1;Down syndrome critical region protein 1;MCIP 1;MCIP1;Modulatory calc
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Synthetic peptide of human RCAN1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody