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Antibodies

LIN28B Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-16187-20UL
60 ul
£183.00
E-AB-16187-60UL
120 ul
£272.00
E-AB-16187-120UL
200 ul
£420.00
E-AB-16187-200UL
About this Product
SKU:
E-AB-16187
Additional Names:
CSDD 2,CSDD2,FLJ16517,LIN28B,LN28B,Lin 28 homolog B (C. elegans),Lin 28.2,Lin-28B,Protein lin-28 homolog B
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Host:
Rabbit
Immunogen:
Synthetic peptide of human LIN28B
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody