MANF Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-16174-20UL
60 ul
£183.00
E-AB-16174-60UL
120 ul
£272.00
E-AB-16174-120UL
200 ul
£420.00
E-AB-16174-200UL
About this Product
- SKU:
- E-AB-16174
- Additional Names:
- ARMET,ARMET protein,ARP,Arginine rich mutated in early stage tumors,Arginine rich protein,Arginine-rich protein,MANF,MGC142148,MGC142150,Manf,Mesencephalic astrocyte derived neurotrophic factor,Mesencephalic astrocyte-derived neurotrophic factor,Protein A
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human MANF
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-manf_polyclonal_antibody-e_ab_16174
