Factor XIIIa Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-16093-20UL
60 ul
£183.00
E-AB-16093-60UL
120 ul
£272.00
E-AB-16093-120UL
200 ul
£420.00
E-AB-16093-200UL
About this Product
- SKU:
- E-AB-16093
- Additional Names:
- A polypeptide;A1 polypeptide);Coagulation factor XIII;Coagulation factor XIII A chain;Coagulation factor XIII A1 polypeptide;Coagulation factor XIII A1 subunit;Coagulation factor XIIIa;F13A;F13a1;Factor XIIIA;Fibri;bA525O21.1 (coagulation factor XIII
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human F13A1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-factor_xiiia_polyclonal_antibody-e_ab_16093
