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Antibodies

CD10 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15992-20UL
60 ul
£183.00
E-AB-15992-60UL
120 ul
£272.00
E-AB-15992-120UL
200 ul
£420.00
E-AB-15992-200UL
About this Product
SKU:
E-AB-15992
Additional Names:
Atriopeptidase,CALLA,CD10,CD10 antigen,Common acute lymphocytic leukemia antigen,DKFZp686O16152,EC 3.4.24.11,EPN,Enkephalinase,Membrane metallo endopeptidase (neutral endopeptidase,enkep,enkephalinase)
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL).This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL.This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb.The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.The coding region is not affected by alternative splicing.
Host:
Rabbit
Immunogen:
Synthetic peptide of human MME
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody