BCAS3 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-15963-20UL
60 ul
£183.00
E-AB-15963-60UL
120 ul
£272.00
E-AB-15963-120UL
200 ul
£420.00
E-AB-15963-200UL
About this Product
- SKU:
- E-AB-15963
- Additional Names:
- 1500019F07Rik,2610028P08Rik,AU021018,BC028339,BCAS3,Breast carcinoma-amplified sequence 3,FLJ20128,GAOB1,K20D4,MAAB,MGC4973,Maab1 protein,rudhira
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- BCAS3 (breast carcinoma amplified sequence 3), also designated MAAB or GAOB1, is a 913 amino acid protein that is believed to be involved in breast cancer progression.The gene is regulated by ER (estrogen receptor alpha) and expressed in multiple tissues, including malignant human brain lesions.It is overexpressed and amplified in breast cancer cell lines.BCAS3 contains three WD40 repeat regions, a bromodomain, a rare zinc-finger motif, four probable DNA-binding domains, and two kinase-inducible phosphorylation domains.Five variants are produced due to alternative splicing.BCAS3 interacts with histone H3 and PCAF, which is indicative of histone acetyltransferase activity.BCAS3 also exhibits ER transactiviation activity by acting as a coactivator with PELP1 or MTA1.The amplification and translocation between the BCAS3 gene and the BCAS4 gene results in a fusion transcript is overexpressed in MCF-7 cells.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human BCAS3
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-bcas3_polyclonal_antibody-e_ab_15963
