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Antibodies

LATS2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15942-20UL
60 ul
£183.00
E-AB-15942-60UL
120 ul
£272.00
E-AB-15942-120UL
200 ul
£420.00
E-AB-15942-200UL
About this Product
SKU:
E-AB-15942
Additional Names:
FLJ13161,KPM,Kinase phosphorylated during mitosis protein,L,LATS large tumor suppressor Drosophila homolog 2,LATS large tumor suppressor homolog 2,Large tumor suppressor homolog 2,Large tumor suppressor homolog 2 Drosophila,Large tumor suppressor kinase 2
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
Host:
Rabbit
Immunogen:
Synthetic peptide of human LATS2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody