SMAD7 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-15853-20UL
60 ul
£183.00
E-AB-15853-60UL
120 ul
£272.00
E-AB-15853-120UL
200 ul
£420.00
E-AB-15853-200UL
About this Product
- SKU:
- E-AB-15853
- Additional Names:
- CRCS3,FLJ16482,MAD,MAD (mothers against decapentaplegic Drosophila) homolog 7,MAD homolog 8,MAD mothers against decapentaplegic homolog 7,MADH 7,MADH 8,MADH6,MADH8,Mad homolog 7,Mother,Mothers Against Decapentaplegic Drosophila Homolog of 6,hSMAD 7,hSMAD7
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human SMAD7
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-smad7_polyclonal_antibody-e_ab_15853
