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Antibodies

POMC Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15786-20UL
60 ul
£183.00
E-AB-15786-60UL
120 ul
£272.00
E-AB-15786-120UL
200 ul
£420.00
E-AB-15786-200UL
About this Product
SKU:
E-AB-15786
Additional Names:
ACTH,Adrenocorticotropic hormone,Adrenocorticotropin,Alpha melanocyte stimulating hormone,Beta LPH,Beta melanocyte stimulating hormone,Beta-endorphin,CLIP,Corticotropin,Corticotropin lipotropin,Corticotropin-like intermediary p,alpha-MSH,alphaMSH,beta-MSH
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.2 mg/ml
Extra Details:
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation.
Host:
Rabbit
Immunogen:
Synthetic peptide of human POMC
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody