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Antibodies

KCNA1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15740-20UL
60 ul
£183.00
E-AB-15740-60UL
120 ul
£272.00
E-AB-15740-120UL
200 ul
£420.00
E-AB-15740-200UL
About this Product
SKU:
E-AB-15740
Additional Names:
AEMK,EA1,Episodic ataxia with myokymia,HBK1,HUK1,KCNA1,KV1.1,Kca1 1,Kcna1,Kcpvd,MBK1,MGC124402,MGC126782,MGC138385,MK1,Potassium,Potassium channel protein 1,Potassium voltage gated channel shaker related subfamily member 1,homolog of KV1.1,mceph,mouse
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Host:
Rabbit
Immunogen:
Synthetic peptide of human KCNA1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody