JNK2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-15735-20UL
60 ul
£183.00
E-AB-15735-60UL
120 ul
£272.00
E-AB-15735-120UL
200 ul
£420.00
E-AB-15735-200UL
About this Product
- SKU:
- E-AB-15735
- Additional Names:
- C Jun N terminal kinase 2,JNK 55,JNK-55,JNK2,JNK2 alpha,JNK2 beta,JNK2A,JNK2B,JNK2BETA,JNK2alpha,Jun kinase,MAP kinase 9,MAPK 9,MK09,Mapk9,Mitogen activated protein kinase 9,Mitogen-activated protein kinase 9,P54a,c Jun kinase 2,c-Jun N-terminal kinase 2
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human MAPK9
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-jnk2_polyclonal_antibody-e_ab_15735
