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Antibodies

GAD2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15661-20UL
60 ul
£183.00
E-AB-15661-60UL
120 ul
£272.00
E-AB-15661-120UL
200 ul
£420.00
E-AB-15661-200UL
About this Product
SKU:
E-AB-15661
Additional Names:
65 kDa glutamic acid decarboxylase,DCE 2,DCE2,GAD 2,GAD 65,GAD-2,GAD-65,Gad2,Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa),Glutamate Decarboxylase 65,Glutamate decarboxyla,Glutamate decarboxylase 2,Glutamate decarboxylase 2 (pancreas)
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Host:
Rabbit
Immunogen:
Synthetic peptide of human GAD2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody