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Antibodies

CK-6A/B/C Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15555-20UL
60 ul
£183.00
E-AB-15555-60UL
120 ul
£272.00
E-AB-15555-120UL
200 ul
£420.00
E-AB-15555-200UL
About this Product
SKU:
E-AB-15555
Additional Names:
CK-6B,CK6A,CK6B,CK6C,CK6D,K6A,K6B,K6C,K6D,K6E,KRT6C,KRT6D,KRT6E,KRTL1,PC2
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Host:
Rabbit
Immunogen:
Synthetic peptide of human KRT6A/KRT6B/KRT6C
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody