Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

BBC3 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15523-20UL
60 ul
£183.00
E-AB-15523-60UL
120 ul
£272.00
E-AB-15523-120UL
200 ul
£420.00
E-AB-15523-200UL
About this Product
SKU:
E-AB-15523
Additional Names:
BBC 3,BBC3,BCL 2 binding component 3,BCL2 binding component 3,Bbc3,Bcl-2-binding component 3,JFY 1,JFY-1,JFY1,PUMA alpha,PUMA/JFY1,p53 Upregulated Modulator of Apoptosis,p53 up regulated modulator of apoptosis,p53 up-regulated modulator of apoptosis
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.9 mg/ml
Extra Details:
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Synthetic peptide of human BBC3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody