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Antibodies

NPR1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15504-20UL
60 ul
£183.00
E-AB-15504-60UL
120 ul
£272.00
E-AB-15504-120UL
200 ul
£420.00
E-AB-15504-200UL
About this Product
SKU:
E-AB-15504
Additional Names:
ANP-A,ANPR-A,ANPRA,ANPa,Atrial natriuretic peptide A type receptor,Atrial natriuretic peptide receptor 1,Atrial natriuretic peptide receptor A,Atrial natriuretic peptide receptor type A,Atrionatriuretic peptide receptor A,GC A,GC-A,Guanylate cyclase
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides, they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2, MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).
Host:
Rabbit
Immunogen:
Synthetic peptide of human NPR1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody