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Antibodies

TNK2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15457-20UL
60 ul
£183.00
E-AB-15457-60UL
120 ul
£272.00
E-AB-15457-120UL
200 ul
£420.00
E-AB-15457-200UL
About this Product
SKU:
E-AB-15457
Additional Names:
ACK,ACK 1,ACK-1,ACK1,Acetate kinase 1,Acetokinase 1,Activated CDC42 kinase 1,Activated Cdc42 associated kinase 1,Activated p21cdc42Hs kinase,FLJ44758,FLJ45547,TNK 2,TNK2,Tyrosine kinase non receptor 2,Tyrosine kinase non receptor protein 2,p21cdc42Hs
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Host:
Rabbit
Immunogen:
Synthetic peptide of human TNK2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody