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Antibodies

DHCR24 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15380-20UL
60 ul
£183.00
E-AB-15380-60UL
120 ul
£272.00
E-AB-15380-120UL
200 ul
£420.00
E-AB-15380-200UL
About this Product
SKU:
E-AB-15380
Additional Names:
24 dehydrocholesterol reductase,24-dehydrocholesterol reductase,3 beta hydroxysterol delta 24 reductase,3-beta-hydroxysterol delta-24-reductase,DCE,DHC24,Delta(24)-sterol reductase,Desmosterol to cholesterol enzyme,Dhcr24,Diminuto dwarf1 homolog,Diminuto
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Host:
Rabbit
Immunogen:
Recombinant protein of human DHCR24
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody