TAB1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-15186-20UL
60 ul
£183.00
E-AB-15186-60UL
120 ul
£272.00
E-AB-15186-120UL
200 ul
£420.00
E-AB-15186-200UL
About this Product
- SKU:
- E-AB-15186
- Additional Names:
- 2310012M03Rik,3'-Tab1,MAP3K7IP 1,MAP3K7IP1,MGC57664,Mitogen activated protein kinase kinase kinase 7 interacting protein 1,Mitogen-activated protein kinase kinase kinase 7-interacting protein 1,TAB 1,TAB1,TAK1 binding protein 1,TAK1-binding protein 1
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human TAB1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-tab1_polyclonal_antibody-e_ab_15186
