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Antibodies

IDH2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15121-20UL
60 ul
£183.00
E-AB-15121-60UL
120 ul
£272.00
E-AB-15121-120UL
200 ul
£420.00
E-AB-15121-200UL
About this Product
SKU:
E-AB-15121
Additional Names:
D2HGA2,ICD-M,IDH,IDH2,IDHM,IDHP,IDP,IDPM,Isocitrate dehydrogenase 2 (NADP+),Isocitrate dehydrogenase [NADP],NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,mNADP-IDH,mitochondrial
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant protein of human IDH2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody