CD42b Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-15083-20UL
60 ul
£183.00
E-AB-15083-60UL
120 ul
£272.00
E-AB-15083-120UL
200 ul
£420.00
E-AB-15083-200UL
About this Product
- SKU:
- E-AB-15083
- Additional Names:
- Antigen CD42b alpha,BDPLT1,BDPLT3,BSS,CD 42b,CD42B,CD42b alpha,CD42b antigen,DBPLT3,GLYCOCALICIN,GP Ib alpha,GP1B,GP1BA,GPIb alpha,GPIbA,Glycoprotein Ib (platelet) alpha polypeptide,Glycoprotein Ibalpha,MGC34595,Platel,Platelet glycoprotein Ib alpha chain
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human GP1BA
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cd42b_polyclonal_antibody-e_ab_15083
