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Antibodies

FLNA Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-15040-20UL
60 ul
£183.00
E-AB-15040-60UL
120 ul
£272.00
E-AB-15040-120UL
200 ul
£420.00
E-AB-15040-200UL
About this Product
SKU:
E-AB-15040
Additional Names:
ABP 280,ABP-280,APBX,Actin-binding protein 280,Alpha filamin,Alpha-filamin,CSBS,CVD1,Endothelial actin binding protein,Endothelial actin-binding protein,FLN,FLN-A,FLN1,FLNA,FMD,Filamin 1,Filamin A,Filamin A alpha,Filamin-1,Filamin-A,MNS,NHBP,Non musc
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.8 mg/ml
Extra Details:
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human FLNA
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody