EID1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-14978-20UL
60 ul
£183.00
E-AB-14978-60UL
120 ul
£272.00
E-AB-14978-120UL
200 ul
£420.00
E-AB-14978-200UL
About this Product
- SKU:
- E-AB-14978
- Additional Names:
- 21 kDa pRb associated protein;21 kDa pRb-associated protein;C15orf3;CBP;CREBBP/EP300 inhibitor 1;CREBBP/EP300 inhibitory protein 1;CRI 1;CRI1;Chromosome 15 open reading frame 3;E1A like inhibitor of differentiation;E1A-like inhibitor of differentiation 1
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human EID1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-eid1_polyclonal_antibody-e_ab_14978
