DCTN4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-14938-20UL
60 ul
£183.00
E-AB-14938-60UL
120 ul
£272.00
E-AB-14938-120UL
200 ul
£420.00
E-AB-14938-200UL
About this Product
- SKU:
- E-AB-14938
- Additional Names:
- DCTN 4,DCTN4,Dctn4,Dynactin 4,Dynactin 4 (p62),Dynactin p62 subunit,Dynactin subunit 4,Dynactin subunit p62,Dynactin4,p62
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DCTN4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dctn4_polyclonal_antibody-e_ab_14938
