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Antibodies

ACLY Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-14775-20UL
60 ul
£183.00
E-AB-14775-60UL
120 ul
£272.00
E-AB-14775-120UL
200 ul
£420.00
E-AB-14775-200UL
About this Product
SKU:
E-AB-14775
Additional Names:
ACL,ACLY,ATP citrate (pro-S) lyase,ATP citrate lyase,ATP citrate synthase,ATP-citrate (pro-S-)-lyase,ATP-citrate synthase,ATPCL,ATPcitrate synthase,Acly,CLATP,Citrate cleavage enzyme,OTTHUMP00000164773
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human ACLY
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody